SCH900776

MedChem Express

SCH900776 [891494-63-6]

10

891494-63-6

Research Use Only

99.97

C15H18BrN7

376.25

SCH900776 (MK-8776) is a potent, selective and orally bioavailable inhibitor of checkpoint kinase1 ( Chk1 ) with an IC 50 of 3 nM. SCH900776 shows 50- and 500-fold selectivity over CDK2 and Chk2, respectively [1] [2] .

NC1=C(Br)C([C@H]2CNCCC2)=NC3=C(C4=CN(C)N=C4)C=NN13

-20°C,2°C to 8°C

12352200