Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using SCN1A Polyclonal Antibody at dilution 1:40
SCN1A/2A/3A/4A/5A/8A/9A/10A/11A/12A Polyclonal Antibody
E-AB-12858
Protein IDP35498
Product group Proteins
Overview
- SupplierElabscience
- Product NameSCN1A/2A/3A/4A/5A/8A/9A/10A/11A/12A Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration0.3mg/ml
- Protein IDP35498
- Protein NameSodium channel protein type 1 subunit alpha
- Scientific DescriptionVoltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.
- UNSPSC12352202