SCR7 [1533426-72-0]

MedChem Express

SCR7 [1533426-72-0]

5

1533426-72-0

Research Use Only

98.22

C18H14N4OS

334.39

SCR7 is an unstable form that can be autocyclized into a stable form SCR7 pyrazine (HY-107845). SCR7 pyrazine is a DNA ligase IV inhibitor that blocks nonhomologous end-joining (NHEJ) in a ligase IV-dependent manner. SCR7 pyrazine increases the efficiency of Cas9-mediated homology-directed repair (HDR). SCR7 pyrazine induces cell apoptosis and has anticancer activity[1][2].

O=C(N1)C(/N=C/C2=CC=CC=C2)=C(NC1=S)/N=C/C3=CC=CC=C3

-20°C,2°C to 8°C

12352200