SCR7 pyrazine [14892-97-8]

MedChem Express

SCR7 pyrazine [14892-97-8]

9

14892-97-8

Research Use Only

99.96

C18H12N4OS

332.38

SCR7 pyrazine is a DNA ligase IV inhibitor that blocks nonhomologous end-joining (NHEJ) in a ligase IV-dependent manner. SCR7 pyrazine is also a CRISPR/Cas9 enhancer which increases the efficiency of Cas9-mediated homology-directed repair (HDR). SCR7 pyrazine induces cell apoptosis and has anticancer activity[1][2].

O=C1NC(NC2=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)N=C12)=S

-20°C,2°C to 8°C

12352200