WB analysis of Daudi cell lysate in (A) the absence and (B) the presence of blocking peptide using GTX85174 SCUBE1 antibody. Working concentration : 1 microg/ml
WB analysis of Daudi cell lysate in (A) the absence and (B) the presence of blocking peptide using GTX85174 SCUBE1 antibody. Working concentration : 1 microg/ml
SCUBE1 antibody
GTX85174
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetSCUBE1
Overview
- SupplierGeneTex
- Product NameSCUBE1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1 microg/mL. ICC/IF: 20 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID80274
- Target nameSCUBE1
- Target descriptionsignal peptide, CUB domain and EGF like domain containing 1
- Target synonymssignal peptide, CUB and EGF-like domain-containing protein 1; signal peptide, CUB domain, EGF-like 1; signal peptide-CUB domain-EGF-related 1
- HostRabbit
- IsotypeIgG
- Protein IDQ8IWY4
- Protein NameSignal peptide, CUB and EGF-like domain-containing protein 1
- Scientific DescriptionSCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity; genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice.
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203