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SDF1 antibody [N1C3]

Research Use Only
GTX116092
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCXCL12
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Overview

  • Supplier
    GeneTex
  • Product Name
    SDF1 antibody [N1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.16 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID6387
  • Target name
    CXCL12
  • Target description
    C-X-C motif chemokine ligand 12
  • Target synonyms
    chemokine (C-X-C motif) ligand 12; intercrine reduced in hepatomas; IRH; PBSF; pre-B cell growth-stimulating factor; SCYB12; SDF1; stromal cell-derived factor 1; TLSF; TPAR1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP48061
  • Protein Name
    Stromal cell-derived factor 1
  • Scientific Description
    For background information on chemokines, see CXCL1 (MIM 155730). Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF (see MIM 191160), or IL1 (see MIM 147760). The intercrines are characterized by the presence of 4 conserved cysteines which form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, which includes beta chemokine, the cysteine residues are adjacent to each other. In the CXC subfamily, which includes alpha chemokine, they are separated by an intervening amino acid. The SDF1 proteins belong to the latter group.[supplied by OMIM]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Experimental Study on the Effect of Allogeneic Endothelial Progenitor Cells on Wound Healing in Diabetic Mice. Leng M et al., 2021, J Diabetes Res
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  • Injection of hybrid 3D spheroids composed of podocytes, mesenchymal stem cells, and vascular endothelial cells into the renal cortex improves kidney function and replenishes glomerular podocytes. Yang WY et al., 2021 May, Bioeng Transl Med
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  • Transplantation of 3D MSC/HUVEC spheroids with neuroprotective and proangiogenic potentials ameliorates ischemic stroke brain injury. Hsu TW et al., 2021 May, Biomaterials
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  • Mobilization of endothelial progenitor cells promotes angiogenesis after full thickness excision by AMD3100 combined with G-CSF in diabetic mice by SDF-1/CXCR4 axis. Lin X et al., 2021 Mar-Apr, Diab Vasc Dis Res
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  • Electroacupuncture at ST36 Increases Bone Marrow-Derived Interstitial Cells of Cajal via the SDF-1/CXCR4 and mSCF/Kit-ETV1 Pathways in the Stomach of Diabetic Mice. Zhao J et al., 2018, Evid Based Complement Alternat Med
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  • High expression of SDF-1 and VEGF is associated with poor prognosis in patients with synovial sarcomas. Feng Q et al., 2018 Mar, Exp Ther Med
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