SDHB antibody [HMV320] HistoMAX(tm)

GeneTex

SDHB antibody [HMV320] HistoMAX(tm)

7

IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

HMV320

0.22 mg/ml

Unconjugated

SDHB

succinate dehydrogenase complex iron sulfur subunit B

CWS2; IP; iron-sulfur subunit of complex II; MC2DN4; PGL4; SDH; SDH1; SDH2; SDHIP; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; succinate dehydrogenase complex, subunit B, iron sulfur (Ip)

Rabbit

IgG

Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352203