Western blot analysis of extracts of various cell lines using SDHB Polyclonal Antibody at 1:500 dilution.
Western blot analysis of extracts of various cell lines using SDHB Polyclonal Antibody at 1:500 dilution.
SDHB Polyclonal Antibody
E-AB-63462
Product group Antibodies
Overview
- SupplierElabscience
- Product NameSDHB Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionComplex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
- UNSPSC12352203