Antibodies

CCR10

Target

Rabbit

Host

GeneTex

Supplier

Monoclonal

Clonality

Unconjugated

Conjugate

Isotype

Research Use Only

Certification

2826

Gene ID

P46092

Protein ID

Bio-Connect Life Sciences

Business unit

This antibody was raised against human CCR10 Extracellular domain.

GTX640123 | CCR10 antibody [HL2852] | GeneTex available at Bio-Connect | Order online now!

CCR10 antibody [HL2852] | GTX640123 | GeneTex

CCR10 antibody [HL2852]

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]

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