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Search results: MAP2K6 MEK6 MKK6

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DNA damage activates TAK1. PSC27 cells were treated with bleomycin, an inducer of DNA strand breaks, with or without increasing concentrations of the TAK1 inhibitor 5Z-7. Cell lysates were immunoprecipitated with an anti-p-TAK1 antibody and subjected to the in vitro kinase assay with MKK6 (OriGene TP304481) as a substrate and radio-labeled ATP. Resulting samples were separated on a 12% SDS-PAGE gel and visualized with autoradiography. Figure cited from Nat Commun, PMID: 29712904
Product group Proteins / Signaling Molecules
OriGene
Protein IDA8K3Y2
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MEK6 (MAP2K6) Human Gene Knockout Kit (CRISPR)
Product group Genome Editing and Engineering
OriGene
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Human MEK6 (MAP2K6) activation kit by CRISPRa
Product group Genome Editing and Engineering
OriGene
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Product group DNA / RNA / Vectors
OriGene
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Product group Expression
OriGene
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Product group Antibodies
Biorbyt
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
ReactivityBovine, Canine, Human, Mouse, Porcine, Rabbit, Rat
TargetMAP2K6
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Product group Antibodies
Biorbyt
MEK6 antibodyORB628749
ApplicationsFlow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry
ReactivityHuman, Mouse, Rat
TargetMAP2K6
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Western blot validation of overexpression lysate (Cat# LY400975) using anti-DDK antibody (Cat# TA50011-100). Left: Cell lysates from un-transfected HEK293T cells; Right: Cell lysates from HEK293T cells transfected with RC204481 using transfection reagent MegaTran 2.0 (Cat# TT210002).
Product group Lysates / Extracts
OriGene
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Western blot validation of overexpression lysate (Cat# LY400975) using anti-DDK antibody (Cat# TA50011-100). Left: Cell lysates from un-transfected HEK293T cells; Right: Cell lysates from HEK293T cells transfected with RC204481 using transfection reagent MegaTran 2.0 (Cat# TT210002).
Product group Lysates / Extracts
OriGene
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Circular map for RC204481
Product group DNA / RNA / Vectors
OriGene
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Circular map for RG204481
Product group DNA / RNA / Vectors
OriGene
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Coomassie blue staining of purified MAP2K6 protein (Cat# TP304481). The protein was produced from HEK293T cells transfected with MAP2K6 cDNA clone (Cat# RC204481) using MegaTran 2.0 (Cat# TT210002).
Product group Assays
OriGene
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