ProductsBack/SEC61B antibody

SEC61B antibody

Name: SEC61B antibody
SKU: GTX129852_G10
Availability: BackOrder

GTX129852

ApplicationsImmunoPrecipitation, Western Blot

Product group Antibodies

ReactivityHuman, Mouse

TargetSEC61B

Overview

Supplier
GeneTex
Product Name
SEC61B antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoPrecipitation, Western Blot
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.77 mg/ml
Conjugate
Unconjugated
Gene ID10952
Target name
SEC61B
Target description
SEC61 translocon subunit beta
Target synonyms
protein translocation complex beta; protein transport protein SEC61 beta subunit; protein transport protein Sec61 subunit beta; Sec61 beta subunit; Sec61 complex, beta subunit; SEC61 translocon beta subunit
Host
Rabbit
Isotype
IgG
Protein IDP60468
Protein Name
Protein transport protein Sec61 subunit beta
Scientific Description
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq]
Reactivity
Human, Mouse
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

H2O2 induces nuclear transport of the receptor tyrosine kinase c-MET in breast cancer cells via a membrane-bound retrograde trafficking mechanism. Chen MK et al., 2019 May 24, J Biol Chem
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