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ProductsBack/Seco-Duocarmycin SA [144667-38-9]

Seco-Duocarmycin SA [144667-38-9]

HY-129356
MedChem Express
Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Seco-Duocarmycin SA [144667-38-9]
  • Delivery Days Customer
    10
  • CAS Number
    144667-38-9
  • Certification
    Research Use Only
  • Molecular Formula
    C25H24ClN3O7
  • Molecular Weight
    513.93
  • Scientific Description
    Seco-Duocarmycin SA is a DNA alkylator. Seco-Duocarmycin SA is an antitumor antibiotic (IC50 = 10 pM). Seco-Duocarmycin SA can induce a concentration-dependent increase in apoptotic cell death. Seco-Duocarmycin SA can lead to significant cell cycle arrest in S and G2/M phases. Seco-Duocarmycin SA acts as an ADC cytotoxin for antibody-drug conjugates[1][2][3].
  • SMILES
    O=C(C1=CC2=C3C(N(C(C(N4)=CC5=C4C(OC)=C(OC)C(OC)=C5)=O)CC3CCl)=CC(O)=C2N1)OC
  • UNSPSC
    41115800

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