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Chemical Structure
Chemical Structure
Chemical Structure

Sekikaic acid [607-11-4]

Research Use Only
AG-CN2-0502
AdipoGen Life Sciences
CAS Number607-11-4
Product group Chemicals
Estimated Purity>96%
Molecular Weight418.4
Price on request
Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Sekikaic acid [607-11-4]
  • Delivery Days Customer
    10
  • CAS Number
    607-11-4
  • Certification
    Research Use Only
  • Estimated Purity
    >96%
  • Molecular Formula
    C22H26O8
  • Molecular Weight
    418.4
  • Scientific Description
    Antioxidant. Reactive oxygen species (ROS) scavenger. Specific ligand of the coactivator CBP/p300, binding to the GACKIX domain. Efficiently inhibits binding of activators at two binding sites. Antibiotic. Potent antibacterial compound. Antifungal on selected fungi species. Antiviral agent. Interferes with the viral replication of selected respiratory syncytial virus. Competitive alpha-glucosidase and non-competitive beta-glucosidase inhibitor. Shows moderate anticancer activity. - Chemical. CAS: 607-11-4. Formula: C22H26O8. MW: 418.4. Isolated from Ramalina sp. Antioxidant. Reactive oxygen species (ROS) scavenger. Specific ligand of the coactivator CBP/p300, binding to the GACKIX domain. Efficiently inhibits binding of activators at two binding sites. Antibiotic. Potent antibacterial compound. Antifungal on selected fungi species. Antiviral agent. Interferes with the viral replication of selected respiratory syncytial virus. Competitive alpha-glucosidase and non-competitive beta-glucosidase inhibitor. Shows moderate anticancer activity.
  • SMILES
    OC1=CC(OC)=CC(CCC)=C1C(OC2=C(OC)C=C(CCC)C(C(O)=O)=C2O)=O
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200

References

  • Phytochemical investigation of the Australian lichens Ramalina glaucescens and Xanthoria parietina: D.A. Dias, et al.; Nat. Prod. Commun. 4, 959 (2009)
  • Antioxidant activities of edible lichen Ramalina conduplicans and its free radical-scavenging constituents: H. Luo, et al.; Mycosci. 51, 391 (2010)
  • Antioxidant activity of some lichen metabolites: V.M. Thadhani, et al.; Nat. Prod. Res. 25, 1827 (2011)
  • Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300: C.Y. Majmudar, et al.; Angew. Chem. Int. Ed. Engl. 51, 11258 (2011)
  • Antimicrobial and toxicological activities of some depsides and depsidones: V.M. Thadhani, et al.; J. Natn. Sci. Found. Sri Lanka 40, 43 (2012)
  • Glucosidase inhibitory and radical scavenging properties of lichen metabolites Salazinic acid, Sekikaic acid and Usnic acid: L.M. Salazinik, et al.; Hacettepe J. Biol. Chem. 40, 7 (2012)
  • Antibacterial and antioxidant activity of lichen species Ramalina roesleri: R. Sisodia, et al.; Nat. Prod. Res. 27, 2235 (2013)
  • Phenolic compounds with in vitro activity against respiratory syncytial virus from the Nigerian lichen Ramalina farinacea: D. Lai, et al.; Planta Med. 79, 1440 (2013)
  • Chemistry and Biological Activity of Ramalina Lichenized Fungi: A.S. Moreira, et al.; Molecules 20, 8952 (2015) (Review)
  • Biopharmaceutical potential of two Ramalina lichens and their metabolites: S. Ristic, et al.; Curr. Pharm. Biotechnol. 17, 651 (2016)