Chemical Structure
Sekikaic acid [607-11-4]
AG-CN2-0502
Overview
- SupplierAdipoGen Life Sciences
- Product NameSekikaic acid
- Delivery Days Customer10
- CAS Number607-11-4
- CertificationResearch Use Only
- Estimated Purity>96%
- Molecular FormulaC22H26O8
- Molecular Weight418.4
- Scientific DescriptionAntioxidant. Reactive oxygen species (ROS) scavenger. Specific ligand of the coactivator CBP/p300, binding to the GACKIX domain. Efficiently inhibits binding of activators at two binding sites. Antibiotic. Potent antibacterial compound. Antifungal on selected fungi species. Antiviral agent. Interferes with the viral replication of selected respiratory syncytial virus. Competitive alpha-glucosidase and non-competitive beta-glucosidase inhibitor. Shows moderate anticancer activity. - Chemical. CAS: 607-11-4. Formula: C22H26O8. MW: 418.4. Isolated from Ramalina sp. Antioxidant. Reactive oxygen species (ROS) scavenger. Specific ligand of the coactivator CBP/p300, binding to the GACKIX domain. Efficiently inhibits binding of activators at two binding sites. Antibiotic. Potent antibacterial compound. Antifungal on selected fungi species. Antiviral agent. Interferes with the viral replication of selected respiratory syncytial virus. Competitive alpha-glucosidase and non-competitive beta-glucosidase inhibitor. Shows moderate anticancer activity.
- SMILESOC1=CC(OC)=CC(CCC)=C1C(OC2=C(OC)C=C(CCC)C(C(O)=O)=C2O)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
References
- Phytochemical investigation of the Australian lichens Ramalina glaucescens and Xanthoria parietina: D.A. Dias, et al.; Nat. Prod. Commun. 4, 959 (2009)
- Antioxidant activities of edible lichen Ramalina conduplicans and its free radical-scavenging constituents: H. Luo, et al.; Mycosci. 51, 391 (2010)
- Antioxidant activity of some lichen metabolites: V.M. Thadhani, et al.; Nat. Prod. Res. 25, 1827 (2011)
- Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300: C.Y. Majmudar, et al.; Angew. Chem. Int. Ed. Engl. 51, 11258 (2011)
- Antimicrobial and toxicological activities of some depsides and depsidones: V.M. Thadhani, et al.; J. Natn. Sci. Found. Sri Lanka 40, 43 (2012)
- Glucosidase inhibitory and radical scavenging properties of lichen metabolites Salazinic acid, Sekikaic acid and Usnic acid: L.M. Salazinik, et al.; Hacettepe J. Biol. Chem. 40, 7 (2012)
- Antibacterial and antioxidant activity of lichen species Ramalina roesleri: R. Sisodia, et al.; Nat. Prod. Res. 27, 2235 (2013)
- Phenolic compounds with in vitro activity against respiratory syncytial virus from the Nigerian lichen Ramalina farinacea: D. Lai, et al.; Planta Med. 79, 1440 (2013)
- Chemistry and Biological Activity of Ramalina Lichenized Fungi: A.S. Moreira, et al.; Molecules 20, 8952 (2015) (Review)
- Biopharmaceutical potential of two Ramalina lichens and their metabolites: S. Ristic, et al.; Curr. Pharm. Biotechnol. 17, 651 (2016)