Selpercatinib-13C,d3

MedChem Express

Selpercatinib-13C,d3

5

Research Use Only

C28 13CH28D3N7O3

529.61

Selpercatinib-13C,d3 (LOXO-292-13C,d3) is 13C labeled Selpercatinib. Selpercatinib (LOXO-292) is a potent, selective RET kinase inhibitor with IC50 values of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M), and RET (G810R), respectively. Selpercatinib has anticancer activity[1][2].

N#CC1=C2C(C3=CC=C(N4CC(C5)N(CC6=CC=C(O[13C]([2H])([2H])[2H])N=C6)C5C4)N=C3)=CC(OCC(C)(O)C)=CN2N=C1

12352200