Selpercatinib

MedChem Express

Selpercatinib [2152628-33-4]

10

2152628-33-4

Research Use Only

99.83

C29H31N7O3

525.60

Selpercatinib (LOXO-292) is a potent, selective RET kinase inhibitor with IC 50 values of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M), and RET (G810R), respectively. Selpercatinib has anticancer activity [1] [2] .

N#CC1=C2C(C3=CC=C(N4CC(C5)N(CC6=CC=C(OC)N=C6)C5C4)N=C3)=CC(OCC(C)(O)C)=CN2N=C1

-20°C,2°C to 8°C

12352200