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Selumetinib (AZD6244)

Research Use Only
S1008
Selleck Chemicals
CAS Number606143-52-6
Product group Chemicals
Estimated Purity...
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Selumetinib (AZD6244) [606143-52-6]
  • Delivery Days Customer
    9
  • CAS Number
    606143-52-6
  • Certification
    Research Use Only
  • Estimated Purity
    ...
  • Scientific Description
    Selumetinib (AZD6244, ARRY-142886) is a potent, highly selective MEK inhibitor with IC50 of 14 nM for MEK1 and Kd value of 530 nM for MEK2. It also inhibits ERK1/2 phosphorylation with IC50 of 10 nM, no inhibition to p38alpha, MKK6, EGFR, ErbB2, ERK2, B-Raf, etc. Selumetinib suppresses cell proliferation, migration and trigger apoptosis. Phase 3.
  • Storage Instruction
    -80°C
  • UNSPSC
    51202000

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