Selumetinib (sulfate)

MedChem Express

Selumetinib (sulfate) [943332-08-9]

10

943332-08-9

99.58

C17H17BrClFN4O7S

555.76

Selumetinib (AZD6244) is selective, non-ATP-competitive oral? MEK1/2 ?inhibitor, with an IC 50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation.

OCCONC(C(C=C1C(N=CN1C)=C2F)=C2NC3=C(C=C(Br)C=C3)Cl)=O.O=S(O)(O)=O

2°C to 8°C

12352200