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Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA613413LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA613413LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA613413LA01HU at dilution of 1:100

SEMA5A Antibody

CSB-PA613413LA01HU
Cusabio
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetSEMA5A
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Overview

  • Supplier
    Cusabio
  • Product Name
    SEMA5A Antibody
  • Delivery Days Customer
    20
  • Applications
    ImmunoFluorescence, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID9037
  • Target name
    SEMA5A
  • Target description
    semaphorin 5A
  • Target synonyms
    sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A; sema F; SEMAF; semaphorin F; semaphorin-5A; semF
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13591
  • Protein Name
    Semaphorin-5A
  • Scientific Description
    Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    41116161

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References
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