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ProductsBack/SEMA5A Antibody

Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA613413LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA613413LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA613413LA01HU at dilution of 1:100

SEMA5A Antibody

CSB-PA613413LA01HU

ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman

TargetSEMA5A

Overview

Supplier
Cusabio
Product Name
SEMA5A Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID9037
Target name
SEMA5A
Target description
semaphorin 5A
Target synonyms
SEMAF, semF, semaphorin-5A, sema F, sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A, semaphorin F
Host
Rabbit
Isotype
IgG
Protein IDQ13591
Protein Name
Semaphorin-5A
Scientific Description
Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis.
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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