Semaphorin-4D/SEMA4D, Human (HEK293, hFc)
HY-P74565
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameSemaphorin-4D/SEMA4D, Human (HEK293, hFc)
- Delivery Days Customer5
- CertificationResearch Use Only
- Estimated Purity97.50
- Gene ID10507
- Target nameSEMA4D
- Target descriptionsemaphorin 4D
- Target synonymsA8, BB18, C9orf164, CD100, COLL4, GR3, M-sema-G, SEMAJ, coll-4, semaphorin-4D, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D
- Scientific DescriptionSemaphorin-4D/SEMA4D protein, a receptor for PLXNB1 and PLXNB2, regulates cell-cell signaling. It promotes inhibitory synapse development via PLXNB1, modulates neurite arborization through RHOA activation, and enhances viability of B-cells. SEMA4D induces endothelial cell migration via PTK2B/PYK2, SRC, and PI3K-AKT pathway. It forms homodimers and interacts with PLXNB2 and PLXNB1. Semaphorin-4D/SEMA4D Protein, Human (HEK293, hFc) is the recombinant human-derived Semaphorin-4D/SEMA4D protein, expressed by HEK293 , with C-hFc labeled tag.
- Storage Instruction-80°C
- UNSPSC41116100
- SpeciesHuman