Sennoside A [81-27-6]

MedChem Express

Sennoside A [81-27-6]

10

81-27-6

Research Use Only

99.66

C42H38O20

862.74

Sennoside A is an anthraquinone glycoside found in senna (Cassia angustifolia). Sennoside A is an HIV-1 inhibitor (IC50=3.8 microM) that inhibits HIV-1 replication. Sennoside A also inhibits HIV-1 reverse transcriptase (RT)-related DNA polymerase (RDDP) and ribonuclease H (Ribonuclease H) with IC50s of 1.9 microM and 5.3 microM, respectively[1][2][3][4].

O=C(C(C=C1[C@@]([C@]2([H])C3=C(C(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)=CC=C3)C(C5=C(O)C=C(C(O)=O)C=C25)=O)([H])C6=C7C(O[C@H]8[C@@H]([C@H]([C@@H]([C@@H](CO)O8)O)O)O)=CC=C6)=CC(O)=C1C7=O)O

2°C to 8°C

12131703