SENP8 antibody [N1N2], N-term

GeneTex

SENP8 antibody [N1N2], N-term

9

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

SENP8

SUMO peptidase family member, NEDD8 specific

DEN1, NEDP1, PRSC2, sentrin-specific protease 8, NEDD8 specific-protease cysteine 2, NEDD8-specific protease 1, SUMO sentrin specific protease family member 8, SUMO/sentrin peptidase family member, NEDD8 specific, SUMO/sentrin specific peptidase family member 8, deneddylase 1, protease, cysteine 2

Rabbit

IgG

Sentrin-specific protease 8

NEDD8 (MIM 603171) is a ubiquitin-like protein that becomes conjugated to the cullin (see CUL1; MIM 603134) subunit of several ubiquitin ligases. This conjugation, called neddylation, is required for optimal ubiquitin ligase activity. NEDD8-specific deneddylases, such as NEDP1, or DEN1, are required to process the NEDD8 propeptide at a C-terminal diglycine motif and to remove NEDD8 from cullins (Gan-Erdene et al., 2003 [PubMed 12759363]).[supplied by OMIM]

-20°C or -80°C,2°C to 8°C

12352203