SensiStain(tm) Anti-CMTM6 Antibody

Applied Biological Materials

SensiStain(tm) Anti-CMTM6 Antibody

9

CMTM6

ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

IHC700

Mouse

IgG1

CMTM6, also referred to as CKLF Like MARVEL Transmembrane Domain Containing 6, is widely expressed in many tissues, but the function relatively remains unknown. SensiStain Anti- CMTM6 Antibody detects the presence of CMTM6 which can be found binding to PD-L1 and maintains its cell surface expression. Studies have showed that due to the binding to PD-L1, CMTM6 co-localizes at plasma membrane and recycling endosomes preventing PD-L1 from being targeted for lysosome-mediated degradation. Due to the high specificity CMTM6 has with PD-L1, it can be studied alongside with PD-L1 as it has a role in suppression of tumour-specific T cell activity.

Human

-20°C,2°C to 8°C

12352203