SensiStain(tm) Anti-Perforin Antibody

Applied Biological Materials

SensiStain(tm) Anti-Perforin Antibody

9

Perforin

ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

IHC646

Mouse

IgG2c

Perforin, a pore-forming protein found in the granules of cytotoxic T-lymphocytes and natural killer cells, functions to enable granzymes to enter the target cells and activate apoptosis. It has been suggested that perforin plays a role in alloimmunity, being involved in both the cytolytic process of rejection as well as downregulation of the T-cell mediated responses associated with the alloimmune response. Perforin-mediated cytotoxicity has also been linked to a number of autoimmune diseases.

Human

-20°C,2°C to 8°C

12352203