axoCells Human iPSC-Derived Sensory Neurons (≥0.5 million cells) for pain and sensation research. Sensory neurons made from iPSCs which were generated from a newborn male donor's cord blood.Key highlights include: • Assay-ready in just 21 days with our Maturation Maximizer media supplement (ax0058)• Expression of the key nociceptive ion channels including Nav1.7 and the DRG-specific, TTX-resistant channels, Nav1.8 and Nav1.9 as well as the temperature-sensitive, TRPV1 and TRPM8, and TRPA1, a sensor of pungency, bitterness and cold• Functional relevance across multiple assays including capsaicin and menthol treatment, thermoception and neurite outgrowth with paclitaxel for a model of chemotherapy-induced peripheral neuropathy• Designed for advanced in vitro model formats including co-culture, microfluidics devices and organ-on-chip platforms• Manufactured in our ISO 9001-accredited production facility with excellent ISSCR Standards complianceWith our axoCells iPSC-derived sensory neurons, you can unlock the benefits of iPSC technology for your in vitro pain and peripheral neurotoxicity models.
