SERCA2 ATPase antibody

GeneTex

SERCA2 ATPase antibody

9

WB: 1:1000 - 1:5000. IP: 1:10 - 1:500. ChIP assay: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

ATP2A2

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2

ATP2B; ATPase Ca++ transporting cardiac muscle slow twitch 2; ATPase, Ca++ dependent, slow-twitch, cardiac muscle-2; calcium pump 2; cardiac Ca2+ ATPase; DAR; DD; endoplasmic reticulum class 1/2 Ca(2+) ATPase; sarcoplasmic/endoplasmic reticulum calcium ATPase 2; SERCA2; SR Ca(2+)-ATPase 2

Rabbit

IgG

Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

2°C to 8°C

12352203