Serpin B9-IN-1 [154235-77-5]
HY-33299
CAS Number154235-77-5
Product group Chemicals
Estimated Purity98.0
Molecular Weight163.13
Overview
- SupplierMedChem Express
- Product NameSerpin B9-IN-1 [154235-77-5]
- Delivery Days Customer5
- CAS Number154235-77-5
- CertificationResearch Use Only
- Estimated Purity98.0
- Hazard Informationh302, h315, h319, h335
- Molecular FormulaC8H5NO3
- Molecular Weight163.13
- Scientific DescriptionSerpin B9-IN-1 (BTCA) is an inhibitor that specifically targets Serpin B9 (SB9); SB9 is a natural inhibitor of granzyme B (GrB) , but may promote the metastasis of lung cancer cells into the bone marrow. SB9-overexpressing cancer cells promote proliferation and metastasis in an immune cell-dependent manner by binding to GrB. Inhibition of SB9 by Serpin B9-IN-1 significantly inhibits immunotherapy of lung cancer bone metastases in the caudal artery (CA) mouse model (LCBM)[1].
- SMILESO=C(C1=CC=C2N=COC2=C1)O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
MSDS
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Product group Chemicals
CAS Number154235-77-5
Estimated Puritymore then97%
Molecular Weight163.13
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Product group Chemicals
CAS Number154235-77-5
Estimated Purity≥95%
Molecular Weight163.13
- SizePrice