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SET, Phosphatase 2A Inhibitor I2PP2A

Research Use Only
X2378B
Nordic-MUbio
Product group Molecular Biology
Price on request
50 ug
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Nordic-MUbio
  • Product Name
    SET, Phosphatase 2A Inhibitor I2PP2A
  • Delivery Days Customer
    7
  • Category Supplier
    Proteins and peptides
  • Certification
    Research Use Only
  • Scientific Description
    Template-activating factor I, TAF-I, HLA-DR-associated protein II, PHAPII, Inhibitor of granzyme A-activated DNase, IGAAD2PP2A; IGAAD; I2PP2A; PHAPII; TAF-IBETA
  • Shelf life instruction
    See expiration date on vial
  • Storage Instruction
    Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
  • UNSPSC
    41116133

References

  • [1] von Lindern M., van Baal S., Wiegant J., Raap A., Hagemeijer A., Grosveld G.; Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene.; Mol. Cell. Biol. 12:3346-3355(1992). [2] von Lindern M., van Baal S., Wiegant J., Raap A., Hagemeijer A., Grosveld G.; Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene.; Mol. Cell. Biol. 12:3346-3355(1992). [3] Vaesen M., Barnikol-Watanabe S., Goetz H., Adil Awni L., Cole T., Zimmermann B., Kratzin H.D., Hilschmann N.; Purification and characterization of two putative HLA class II associated proteins: PHAPI and PHAPII.; Biol. Chem. Hoppe-Seyler 375:113-126(1994). [4] Nagata K., Kawase H., Handa H., Yano K., Yamasaki M., Ishimi Y., Okuda A., Kikuchi A., Matsumoto K.; Replication factor encoded by a putative oncogene, set, associated with myeloid leukemogenesis.; Proc. Natl. Acad. Sci. U.S.A. 92:4279-4283(1995). [5] Li M., Makkinje A., Damuni Z.; The myeloid leukemia-associated protein SET is a potent inhibitor of protein phosphatase 2A.; J. Biol. Chem. 271:11059-11062(1996). [6] Tsujio I., Zaidi T., Xu J., Kotula L., Grundke-Iqbal I., Iqbal K.; Inhibitors of protein phosphatase-2A from human brain: structures, immunocytological localization and activities towards dephosphorylation of the Alzheimer type hyperphosphorylated Tau.; Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. [7] The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).; Genome Res. 14:2121-2127(2004). [8] Adachi Y., Pavlaki G.N., Copeland T.D.; Identification and characterization of SET, a nuclear phosphoprotein encoded by the translocation break point in acute undifferentiated leukemia.; J. Biol. Chem. 269:2258-2262(1994). [9] Wang L.C., Chen Y.; A relative factor in human rectum carcinoma.; Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases. [10] Carlson S.G., Eng E., Kim E.-G., Perlman E.J., Copeland T.D., Ballermann B.J.; Expression of SET, an inhibitor of protein phosphatase 2A, in renal development and Wilms' tumor.; J. Am. Soc. Nephrol. 9:1873-1880(1998). [11] Seo S.-B., McNamara P., Heo S., Turner A., Lane W.S., Chakravarti D.; Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the Set oncoprotein.; Cell 104:119-130(2001). [12] Minakuchi M., Kakazu N., Gorrin-Rivas M.J., Abe T., Copeland T.D., Ueda K., Adachi Y.; Identification and characterization of SEB, a novel protein that binds to the acute undifferentiated leukemia-associated protein SET.; Eur. J. Biochem. 268:1340-1351(2001). [13] Fan Z., Beresford P.J., Zhang D., Lieberman J.; HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A.; Mol. Cell. Biol. 22:2810-2820(2002). [14] Fan Z., Beresford P.J., Oh D.Y., Zhang D., Lieberman J.; Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor.; Cell 112:659-672(2003). [15] Fan Z., Beresford P.J., Oh D.Y., Zhang D., Lieberman J.; Cell 115:241-241(2003). [16] Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.; Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.; Cell 127:635-648(2006). [17] Sprung R., Chen Y., Xu Y., Ball H., Pei J., Cheng T., Kho Y., Xiao H., Xiao L., Grishin N.V., White M., Yang X.-J., Zhao Y.; Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.; Mol. Cell 23:607-618(2006). [18] Molina H., Horn D.M., Tang N., Mathivanan S., Pandey A.; Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry.; Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007).