Bio-Connect

SETD6 antibody [GT688]

GTX629891
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetSETD6
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Overview

  • Supplier
    GeneTex
  • Product Name
    SETD6 antibody [GT688]
  • Delivery Days Customer
    9
  • Antibody Specificity
    Knockdown/Knockout validation was supported by references (PMID:35694846)
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    GT688
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID79918
  • Target name
    SETD6
  • Target description
    SET domain containing 6, protein lysine methyltransferase
  • Target synonyms
    N-lysine methyltransferase SETD6; SET domain-containing protein 6
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDQ8TBK2
  • Protein Name
    N-lysine methyltransferase SETD6
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Methylation of the transcription factor E2F1 by SETD6 regulates SETD6 expression via a positive feedback mechanism.
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  • TWIST1 methylation by SETD6 selectively antagonizes LINC-PINT expression in glioma.
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  • BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation. Vershinin Z et al., 2021 May, Sci Adv
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  • PAK4 methylation by the methyltransferase SETD6 attenuates cell adhesion. Vershinin Z et al., 2020 Oct 13, Sci Rep
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  • Enterovirus pathogenesis requires the host methyltransferase SETD3. Diep J et al., 2019 Dec, Nat Microbiol
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  • Peptide inhibition of the SETD6 methyltransferase catalytic activity. Feldman M et al., 2018 Jan 12, Oncotarget
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  • PAK4 Methylation by SETD6 Promotes the Activation of the Wnt/beta-Catenin Pathway. Vershinin Z et al., 2016 Mar 25, J Biol Chem
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