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SETD6 antibody [GT688]

Name: SETD6 antibody [GT688]
SKU: GTX629891_G10
Availability: BackOrder

GTX629891

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman

TargetSETD6

Overview

Supplier
GeneTex
Product Name
SETD6 antibody [GT688]
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
GT688
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID79918
Target name
SETD6
Target description
SET domain containing 6, protein lysine methyltransferase
Target synonyms
N-lysine methyltransferase SETD6, SET domain-containing protein 6
Host
Mouse
Isotype
IgG2b
Protein IDQ8TBK2
Protein Name
N-lysine methyltransferase SETD6
Reactivity
Human
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Kublanovsky M, Ulu GT, Weirich S, et al. Methylation of the transcription factor E2F1 by SETD6 regulates SETD6 expression via a positive feedback mechanism. J Biol Chem. 2023,299(10):105236. doi: 10.1016/j.jbc.2023.105236
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Admoni-Elisha L, Elbaz T, Chopra A, et al. TWIST1 methylation by SETD6 selectively antagonizes LINC-PINT expression in glioma. Nucleic Acids Res. 2022,50(12):6903-6918. doi: 10.1093/nar/gkac485
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Vershinin Z, Feldman M, Werner T, et al. BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation. Sci Adv. 2021,7(22). doi: 10.1126/sciadv.abf5374
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Vershinin Z, Feldman M, Levy D. PAK4 methylation by the methyltransferase SETD6 attenuates cell adhesion. Sci Rep. 2020,10(1):17068. doi: 10.1038/s41598-020-74081-1
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Diep J, Ooi YS, Wilkinson AW, et al. Enterovirus pathogenesis requires the host methyltransferase SETD3. Nat Microbiol. 2019,4(12):2523-2537. doi: 10.1038/s41564-019-0551-1
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Feldman M, Levy D. Peptide inhibition of the SETD6 methyltransferase catalytic activity. Oncotarget. 2018,9(4):4875-4885. doi: 10.18632/oncotarget.23591
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Vershinin Z, Feldman M, Chen A, et al. PAK4 Methylation by SETD6 Promotes the Activation of the Wnt/β-Catenin Pathway. J Biol Chem. 2016,291(13):6786-95. doi: 10.1074/jbc.M115.697292
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