SETMAR Polyclonal Antibody

Reddot Biotech

SETMAR Polyclonal Antibody

5

1.08 mg/ml

SETMAR

SET domain and mariner transposase fusion gene

histone-lysine N-methyltransferase SETMAR; Mar1; METNASE; SET domain and mariner transposase fusion gene-containing protein; SET domain and mariner transposase fusion protein

This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.

-20°C

12352203