SEW 2871 [256414-75-2]

TargetMol Chemicals

SEW 2871 [256414-75-2]

4

256414-75-2

Chemical

Research Use Only

SEW​2871

99.62%

C20H10F6N2OS

440.36

SEW 2871 is an orally available, highly selective S1P1 agonist with an EC50 of 13.8 nM.It reduces the number of lymphocytes in the blood and is used in studies related to diabetes, Alzheimers disease, liver fibrosis, and inflammation. It activates ERK, Akt and Rac signaling pathways and induces S1P1 internalization and recycling.

3 years

FC(F)(F)c1sc(cc1-c1ccccc1)-c1nc(no1)-c1cccc(c1)C(F)(F)F

-20°C

12352200