SF3B1 antibody

GeneTex

SF3B1 antibody

9

WB: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

SF3B1

splicing factor 3b subunit 1

Hsh155, MDS, PRP10, PRPF10, SAP155, SF3b155, splicing factor 3B subunit 1, pre-mRNA processing 10, pre-mRNA splicing factor SF3b, 155 kDa subunit, spliceosome-associated protein 155, splicing factor 3b, subunit 1, 155kDa

Rabbit

IgG

Splicing factor 3B subunit 1

This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the introns branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352203