Bio-Connect

SGC0946

HY-15650
MedChem Express
CAS Number1561178-17-3
Product group Chemicals
Estimated Purity99.68
Molecular Weight618.57
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    MedChem Express
  • Product Name
    SGC0946 [1561178-17-3]
  • Delivery Days Customer
    10
  • CAS Number
    1561178-17-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.68
  • Molecular Formula
    C28H40BrN7O4
  • Molecular Weight
    618.57
  • Scientific Description
    SGC0946 is a selective DOT1LH3K79 methyltransferase) inhibitor, with an IC50 of 0.3 nM. SGC0946 results in G1 arrest, inhibits potential of cell self-renewal and metastatic, also induces cell differentiation. SGC0946 can be used in studies of leukemia and solid tumors and also serve as a probe to further investigate the cellular mechanism of DOT1L in both normal and diseased cells[1][2][3].
  • SMILES
    NC1=NC=NC2=C1C(Br)=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CN(CCCNC(NC4=CC=C(C(C)(C)C)C=C4)=O)C(C)C)O3
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

Related products

SGC0946 [1561178-17-3]
Product group Chemicals
TargetMol Chemicals
CAS Number1561178-17-3
Estimated Purity99.82%
Molecular Weight618.57
  • SizePrice
Product group Chemicals
Biorbyt
SGC0946ORB1304559
CAS Number1561178-17-3
Estimated Purity99.82%
Molecular Weight618.57
  • SizePrice
Product group Chemicals
AbMole BioScience
SGC0946M7578
CAS Number1561178-17-3
Molecular Weight618.57
  • SizePrice
Product group Chemicals
Santa Cruz Biotechnology
CAS Number1561178-17-3
  • SizePrice
Product group Chemicals
RayBiotech
SGC 0946331-10940
  • SizePrice