SGI-1776 free base [1025065-69-3]

BPS Bioscience

SGI-1776 free base

7

1025065-69-3

Research Use Only

≥98%

C20H22F3N5O

405.4 Da

SGI-1776 is a potent ATP-competitive inhibitor of the serine/threonine family of Pim kinase, an enzyme regulating cell survival. Through extensive biomedical characterization, SGI-1776 exhibits specificity to the three isoforms of the Pim family, including Pim-1, Pim-2, and Pim-3. Treatment with SGI-1776 induces apoptosis in CLL primary cell line.

-20°C

51202000