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Western Blot Positive WB detected in: K562 whole cell lysate All lanes: SGMS1 antibody at 4microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 49, 26 kDa Observed band size: 49 kDa
Western Blot Positive WB detected in: K562 whole cell lysate All lanes: SGMS1 antibody at 4microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 49, 26 kDa Observed band size: 49 kDa
Western Blot Positive WB detected in: K562 whole cell lysate All lanes: SGMS1 antibody at 4microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 49, 26 kDa Observed band size: 49 kDa

SGMS1 Antibody

CSB-PA801243LA01HU
Cusabio
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetSGMS1
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Overview

  • Supplier
    Cusabio
  • Product Name
    SGMS1 Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID259230
  • Target name
    SGMS1
  • Target description
    sphingomyelin synthase 1
  • Target synonyms
    hmob33; medulla oblongata-derived protein; MOB; MOB1; phosphatidylcholine:ceramide cholinephosphotransferase 1; protein Mob; SMS1; TMEM23; transmembrane protein 23
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ86VZ5
  • Protein Name
    Phosphatidylcholine:ceramide cholinephosphotransferase 1
  • Scientific Description
    Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    41116161

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