SGMS2 Antibody

Cusabio

SGMS2 Antibody

20

ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

SGMS2

sphingomyelin synthase 2

CDL; phosphatidylcholine:ceramide cholinephosphotransferase 2; SM synthase; SMS2

Rabbit

IgG

Phosphatidylcholine:ceramide cholinephosphotransferase 2

Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Plasma membrane SMS2 can also convert phosphatidylethanolamine (PE) to ceramide phosphatidylethanolamine (CPE). Major form in liver. Required for cell growth in certain cell types. Regulator of cell surface levels of ceramide, an important mediator of signal transduction and apoptosis. Regulation of sphingomyelin (SM) levels at the cell surface affects insulin sensitivity.

Human, Rat

-20°C or -80°C

41116161