SGX-523

MedChem Express

SGX-523 [1022150-57-7]

10

1022150-57-7

Research Use Only

99.23

C18H13N7S

359.41

SGX523 is a exquisitely selective and ATP-competitive MET inhibitor. SGX523 potently inhibits MET with an IC 50 of 4 nM and is >1,000-fold selective versus other protein kinases. Antitumor activity [1] .

CN1N=CC(C2=NN3C(SC4=CC5=C(N=CC=C5)C=C4)=NN=C3C=C2)=C1

-20°C,2°C to 8°C

12352200