IHC-P analysis of human lung tissue using GTX85017 SH3BP4 antibody. Working concentration : 5 microg/ml
IHC-P analysis of human lung tissue using GTX85017 SH3BP4 antibody. Working concentration : 5 microg/ml
SH3BP4 antibody
GTX85017
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSH3BP4
Overview
- SupplierGeneTex
- Product NameSH3BP4 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1 - 2 microg/mL. IHC-P: 5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID23677
- Target nameSH3BP4
- Target descriptionSH3 domain binding protein 4
- Target synonymsBOG25; EH-binding protein 10; SH3 domain-binding protein 4; transferrin receptor-trafficking protein; TTP
- HostRabbit
- IsotypeIgG
- Protein IDQ9P0V3
- Protein NameSH3 domain-binding protein 4
- Scientific DescriptionSH3BP4 was initially isolated as a novel cDNA using differential display analysis using cultured human corneal fibroblasts. The protein contains three Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. SH3BP4 has been shown to interact with specific endocytic proteins such as clathrin, dynamin, and the transferrin receptor (TfR) and localizes to TfR-containing coated pits and vesicles. It is thought to be involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of TfR. At least two isoforms of SH3BP4 are known to exist.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203