SHH, Human (C24IVI)

MedChem Express

SHH, Human (C24IVI)

10

Research Use Only

95.00

SHH

sonic hedgehog signaling molecule

HHG1; HLP3; HPE3; MCOPCB5; shh unprocessed N-terminal signaling and C-terminal autoprocessing domains; ShhNC; SMMCI; sonic hedgehog homolog; sonic hedgehog protein; TPT; TPTPS

Sonic hedgehog protein

Sonic Hedgehog (SHH) Protein is a secretory glycoprotein of the Hedgehog family that can self-cleave to form N-SHH. SHH Protein activates Smo by binding to Frizzled and LRP6, inhibits GSK-3beta to stabilize beta-catenin, and activates FOXM1. SHH Protein also promotes NO release and shortens myocardial APD by phosphorylating eNOS through PI3K/Akt. SHH Protein can promote the maturation of sweat gland cells in three-dimensional culture and play a cardioprotective role in the pig ischemia-reperfusion model[1][2]. SHH Protein, Human (C24IVI) is a recombinant human SHH protein expressed in E. coli with C24IVI-mutation and tag-free.

-20°C

41116100