Bio-Connect

Shield-2 [1013621-70-9]

HY-113646
MedChem Express
CAS Number1013621-70-9
Product group Chemicals
Molecular Weight625.80
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Shield-2 [1013621-70-9]
  • Delivery Days Customer
    9
  • CAS Number
    1013621-70-9
  • Certification
    Research Use Only
  • Molecular Formula
    C35H51N3O7
  • Molecular Weight
    625.80
  • Scientific Description
    Shield-2 is an efficient stabilizing ligand binding to the FKBP (F36V) protein with a dissociation constant of 29 nM. Shield-2 binds tightly to the FKBP mutants destabilizing domains and prevents degradation, thus providing small molecule regulation over intracellular protein levels[1][2].
  • SMILES
    COC(C=C1CC[C@H](C2=CC(OCCN3CCOCC3)=CC=C2)OC([C@H]4N(CCCC4)C(NC(CC)CC)=O)=O)=C(C=C1)OC
  • UNSPSC
    12352200