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ShK-Dap22 [220384-25-8]

ShK-Dap22 [220384-25-8]

TP2123
TargetMol Chemicals
CAS Number220384-25-8
DownloadMSDS
Product group Chemicals
Molecular Weight4012.7
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    ShK-Dap22 [220384-25-8]
  • Delivery Days Customer
    44
  • CAS Number
    220384-25-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    ShK-Dap22
  • Molecular Formula
    C166H268N54O48S7
  • Molecular Weight
    4012.7
  • Scientific Description
    Extremely potent KV1.3 channel blocker (Kd = 23 pM for mKV1.3 currents). Selective for KV1.3 over other mammalian potassium channels (IC50 values are 23, 1800, 10500, 37000 and 39000 pM for mKV1.3, mKV1.1, hKV1.6, mKV1.4 and rKV1.2 respectively, and >100000 pM for hKV1.5, mKV1.7, hKV3.1, rKV3.4 and hKCa4). Suppresses T cell activation in vitro (IC50 < 500 pM).
  • Shelf life instruction
    3 years
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200