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SHP099

HY-100388
MedChem Express
CAS Number1801747-42-1
Product group Chemicals
Estimated Purity99.81
Molecular Weight352.26
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Overview

  • Supplier
    MedChem Express
  • Product Name
    SHP099 [1801747-42-1]
  • Delivery Days Customer
    10
  • CAS Number
    1801747-42-1
  • Estimated Purity
    99.81
  • Molecular Formula
    C16H19Cl2N5
  • Molecular Weight
    352.26
  • Scientific Description
    SHP099 is an allosteric SHP2 inhibitor, with IC 50 s of 0.690, 1.241, 0.416, 1.968, 2.896 microM for SHP2, SHP2 D61Y , SHP2E69K, SHP2 A72V , SHP2 E76K . SHP099 inhibits cancer cell growth, such as MV4-11 and TF-1 cell (IC 50 : 0.32 and 1.73 microM). SHP099 inhibits RAS-ERK signaling and inhibits tumor growth [1] [2] .
  • SMILES
    NC1=NC(N2CCC(C)(N)CC2)=CN=C1C3=CC=CC(Cl)=C3Cl
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200