SHP099 (Standard) [1801747-42-1]

MedChem Express

SHP099 (Standard) [1801747-42-1]

5

Research Use Only

SHP099 (Standard) is the analytical standard of SHP099. This product is intended for research and analytical applications. SHP099 is an allosteric SHP2 inhibitor, with IC50s of 0.690, 1.241, 0.416, 1.968, 2.896 microM for SHP2, SHP2D61Y, SHP2E69K, SHP2A72V, SHP2E76K. SHP099 inhibits cancer cell growth, such as MV4-11 and TF-1 cell (IC50: 0.32 and 1.73 microM). SHP099 inhibits RAS-ERK signaling and inhibits tumor growth[1][2].

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