SHP2-IN-22 [2802453-88-7]

MedChem Express

SHP2-IN-22 [2802453-88-7]

14

2802453-88-7

Research Use Only

C23H22Cl2N8O

497.38

SHP2-IN-22 is SHP2 allosteric inhibitor with an IC50 value of 17.7 nM. SHP2-IN-22 inhibits the proliferation, migration, and invasion of MIA PaCa-2 pancreatic cancer cells. SHP2-IN-22 can be used for Kirsten rat sarcoma viral oncogene (KRAS) mutant cancer research[1].

N/C(N1CCN(CC1)C2=CN=C(C(N)=N2)C3=CC=CC(Cl)=C3Cl)=N\C4=CC(OC)=C(C=C4)C#N

12131703