SHP2-IN-9

MedChem Express

SHP2-IN-9

10

Research Use Only

98.68

C20H20FN3O2S

385.46

SHP2-IN-9 is a specific SHP2 inhibitor (IC50 =1.174 microM) with enhanced blood-brain barrier penetration. SHP2-IN-9 shows 85-fold more selective for SHP2 than SHP1. SHP2-IN-9 inhibits SHP2-mediated cell signal transduction and cancer cell proliferation, and inhibits the growth of cervix cancer tumors and glioblastoma growth in vivo[1].

O=C(NCC1=CC=C(C=C1)F)CN2C=NC3=C(C4=C(S3)CCCCC4)C2=O

-20°C,2°C to 8°C

12352200