SIAIS164018 hydrochloride

TargetMol Chemicals

SIAIS164018 hydrochloride

999

Research Use Only

SIAIS164018 hydrochloride

C43H49Cl2N10O7P

919.79

SIAIS164018 hydrochloride is a PROTAC-based degrader targeting ALK and EGFR, exhibiting IC50 values of 2.5 nM for ALK and 6.6 nM for ALK G1202R. It effectively suppresses cancer cell migration and invasion, induces G1 cell cycle arrest, and promotes apoptosis, demonstrating superior properties compared to Brigatinib [1].

3 years

-20°C

12352200