More than 130 suppliers

In-house tech support

Call +31 (0)26 326 44 50

Bio-Connect

Products
Products
Antibodies
Chemicals
Proteins / Signaling Molecules
Assays
DNA / RNA / Vectors
Cell Culture
Genome Editing and Engineering
Molecular Biology
Lysates / Extracts
Expression
Labware / Accesories
Body Products
Technique Specific Products
Arrays / Slides
Diagnostic
Biologicals
Microbiology
Promotions
All product groups
Support your research
For 15 years, we connect life science researchers specialized in the import and distribution of life science reagents from global suppliers.
How can we help?
Suppliers
Suppliers
Life Sciences
Diagnostics
Services
Become a partner
All Suppliers
Support your research
For 15 years, we connect life science researchers specialized in the import and distribution of life science reagents from global suppliers.
How can we help?
Industries
Industries
Biotech, Pharma & CRO
Academia
Diagnostics
Environment
Food
Veterinary
All industries
Support your research
For 15 years, we connect life science researchers specialized in the import and distribution of life science reagents from global suppliers.
How can we help?
News

Website
Events
Promotions
About us
About us
Our company
Our team
For suppliers
Vacatures
Events
Promotions
Support your research
For 15 years, we connect life science researchers specialized in the import and distribution of life science reagents from global suppliers.
How can we help?
Contact
Contact
Headquarters
Customer Service
Technical support
Accountmanagers
FAQ
Support your research
For 15 years, we connect life science researchers specialized in the import and distribution of life science reagents from global suppliers.
How can we help?

ProductsBack/Sibiriline [1346526-26-8]

Sibiriline [1346526-26-8]

HY-120600

CAS Number1346526-26-8

Product group Chemicals

Molecular Weight210.23

Overview

Supplier
MedChem Express
Product Name
Sibiriline [1346526-26-8]
Delivery Days Customer
5
CAS Number
1346526-26-8
Certification
Research Use Only
Hazard Information
h302-h315-h319-h335,p261-p264-p270-p271-p280-p302+p352-p304+p340-p305+p351+p338-p330-p362+p364-p403+p233-p405-p501
Molecular Formula
C13H10N2O
Molecular Weight
210.23
Scientific Description
Sibiriline is a specific competitive inhibitor of RIPK1 that targets the RIPK1 ATP-binding site and locks it in an inactive conformation. Sibiriline inhibits TNF-induced RIPK1-dependent necroptosis and RIPK1-dependent apoptosis, but does not protect cells from caspase-dependent apoptosis. Sibiriline protects mice from concanavalin A-induced hepatitis and has the potential to inhibit immune-dependent hepatitis.[1].
SMILES
OC1=CC=C(C=C1)C2=CC3=CC=CN=C3N2
UNSPSC
12352200

MSDS

FAQ

Go to our frequently asked questions