
Western blot All lanes: SIGIRR antibody at 1.77microg/ml Lane 1: Mouse liver tissue Lane 2: Mouse kidney tissue Lane 3: MCF-7 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 46, 56 kDa Observed band size: 46 kDa
SIGIRR Antibody
CSB-PA743558ESR1HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetSIGIRR
Overview
- SupplierCusabio
- Product NameSIGIRR Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID59307
- Target nameSIGIRR
- Target descriptionsingle Ig and TIR domain containing
- Target synonymsIL-1R8; single Ig IL-1-related receptor; single Ig IL-1R-related molecule; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; single immunoglobulin domain IL1R1 related; single immunoglobulin domain-containing IL1R-related protein; TIR8; toll/interleukin-1 receptor 8
- HostRabbit
- IsotypeIgG
- Protein IDQ6IA17
- Protein NameSingle Ig IL-1-related receptor
- Scientific DescriptionActs as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC41116161