SIGIRR, Mouse (HEK293, His)

MedChem Express

SIGIRR, Mouse (HEK293, His)

10

Research Use Only

95.0

Sigirr

single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

TIR8, single Ig IL-1-related receptor, single Ig IL-1 receptor related protein, single Ig IL-1R-related molecule, single Ig IL-1R-related protein, single immunoglobulin domain-containing IL1R-related protein, toll/interleukin-1 receptor 8

Single Ig IL-1-related receptor

SIGIRR protein negatively regulates the Toll-like pathway and IL-1R pathway by inhibiting the recruitment of TLR4.SIGIRR disrupts Il1R1 and IL1RAP heterodimerization through its extracellular domain.SIGIRR Protein, Mouse (HEK293, His-hFc) is the recombinant mouse-derived SIGIRR protein, expressed by HEK293 , with C-hFc, C-His labeled tag.

-20°C

41116100