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Siglec-3/CD33, Cynomolgus/Rhesus Macaque (HEK293, His)

Name: Siglec-3/CD33, Cynomolgus/Rhesus Macaque (HEK293, His)
SKU: HY-P75651_M09
Availability: BackOrder

HY-P75651

Protein IDA0A2K5W2R5

Product group Proteins / Signaling Molecules

Overview

Supplier
MedChem Express
Product Name
Siglec-3/CD33, Cynomolgus/Rhesus Macaque (HEK293, His)
Delivery Days Customer
10
Certification
Research Use Only
Estimated Purity
96.00
Gene ID102117580
Target name
CD33
Target description
CD33 molecule
Target synonyms
myeloid cell surface antigen CD33
Protein IDA0A2K5W2R5
Protein Name
Ig-like domain-containing protein
Scientific Description
Siglec-3/CD33, a sialic-acid-binding lectin, crucially mediates cell-cell interactions and immune cell quiescence. Preferring sialic acid on specific mucins, it forms homodimers, interacting with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation. CD33 also engages C1QA through its C-terminus, activating CD33 inhibitory motifs. Siglec-3/CD33 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived Siglec-3/CD33 protein, expressed by HEK293 , with C-His labeled tag.
Storage Instruction
-20°C
UNSPSC
41116100
Species
Primate